During a retrovirus infection, a DNA copy of the viral RNA genome is permanently integrated into the nuclear DNA of the host cell as a provirus. Endogenous retroviruses (ERVs) have contributed to more than 8% of the human genome.
This project’s goal is to locate endogenous retroviruses DNA copies into host’s genome and their lineage and then to consider whether is a mutation in genes close to and what the consequences are.
People: Yiannis Koutsoukos